Colorectal cancer (CRC)  is the 3^rd most common type of cancer worldwide and its occurrence is increasing, especially in populations with lower socioeconomic status, due to unhealthy dietary habits and lifestyle among others. The research project ‘ONCODIR: Evidence-based Participatory Decision Making for Cancer Prevention through implementation’ will identify risk factors associated with colorectal cancer and will integrate multidisciplinary research methods and technologies (including health policy analytics, artificial intelligence and decision support theories) to deliver evidence-based and personalised recommendations on colorectal cancer prevention.